Background:

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.

Applications:

ELISA, WB, IHC

Name of antibody:

TUBB3

Immunogen:

Fusion protein of human TUBB3

Full name:

tubulin beta 3 class III

Synonyms:

CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A

SwissProt:

Q13509

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human cervical cancer and Human tonsil

IHC Recommend dilution:

30-150

WB Predicted band size:

50 kDa

WB Positive control:

Hela, A549 and PC-3 cell lysates

WB Recommended dilution:

1000-5000