Background:

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.

Applications:

WB, IHC

Name of antibody:

MCPH1

Immunogen:

Synthesized peptide derived from internal of human MCPH1.

Full name:

microcephalin 1

Synonyms：

MCT; BRIT1

SwissProt:

Q8NEM0

IHC positive control:

Human thymus glan tissue

IHC Recommend dilution:

50-100

WB Predicted band size:

93 kDa

WB Positive control:

K562 cells lysate

WB Recommended dilution:

500-3000