Full name:

PDZ and LIM domain 2 (mystique)

Synonyms:

SLIM; MYSTIQUE

Swissprot:

Q96JY6

Gene Accession:

BC021556

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and ***** T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.